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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
33.94
Human Site:
S478
Identified Species:
57.44
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
S478
S
A
F
L
K
V
S
S
V
F
K
D
E
A
T
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
S478
S
A
F
L
K
V
S
S
V
F
K
D
E
A
T
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
S532
S
A
F
L
K
V
S
S
V
F
K
D
E
A
A
Dog
Lupus familis
XP_538355
1323
142434
S478
S
A
F
L
K
V
S
S
V
F
K
D
E
A
P
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
S480
S
A
F
L
K
V
A
S
V
F
R
D
D
A
S
Rat
Rattus norvegicus
NP_001012199
431
46388
D327
K
A
E
L
E
K
L
D
L
N
G
N
A
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
S480
S
T
F
L
K
V
S
S
V
L
K
D
D
V
S
Chicken
Gallus gallus
NP_001006237
580
63057
S471
T
A
L
L
R
I
S
S
V
F
K
D
E
A
Q
Frog
Xenopus laevis
O13066
580
62889
S471
Q
A
F
I
Q
V
S
S
V
Y
R
E
D
G
E
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
S456
E
A
F
L
K
I
S
S
V
Y
K
D
N
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
A481
D
M
D
N
K
L
E
A
L
Q
S
I
V
N
Q
Honey Bee
Apis mellifera
XP_395378
580
63771
K455
E
Y
T
R
I
I
M
K
V
S
A
L
S
T
S
Nematode Worm
Caenorhab. elegans
P34342
960
105635
T637
A
T
F
K
A
L
E
T
V
E
W
F
D
V
R
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
A283
S
E
G
A
D
A
I
A
N
S
L
R
E
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
13.3
N.A.
66.6
66.6
40
60
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
100
33.3
N.A.
80
86.6
80
73.3
N.A.
26.6
20
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
65
0
8
8
8
8
15
0
0
8
0
8
43
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
0
8
0
0
0
58
29
8
0
% D
% Glu:
15
8
8
0
8
0
15
0
0
8
0
8
43
0
8
% E
% Phe:
0
0
65
0
0
0
0
0
0
43
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
8
0
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
22
8
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
8
58
8
0
8
0
0
50
0
0
0
0
% K
% Leu:
0
0
8
65
0
15
8
0
15
8
8
8
0
8
0
% L
% Met:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
8
0
8
8
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
15
% Q
% Arg:
0
0
0
8
8
0
0
0
0
0
15
8
0
0
8
% R
% Ser:
50
0
0
0
0
0
58
65
0
15
8
0
8
0
22
% S
% Thr:
8
15
8
0
0
0
0
8
0
0
0
0
0
8
15
% T
% Val:
0
0
0
0
0
50
0
0
79
0
0
0
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _